Researcher/Scientist III, Translational Cardiovascular Research Center (Phoenix)

This position involves generating research hypotheses using controlled investigations, experiments and/or trials for research on cardiovascular disease using animal models of cardiovascular diseases, e.g. Ischemic heart diseases, diabetic cardiomyopathy, heart failure, coronary microvascular dysfunction, with a goal toward translating basic science findings to clinically viable potential therapeutics. The position is best suited for those well trained in in vivo animal models with strong background in cardiovascular physiology, vascular biology, coronary microcirculation and who is detailed oriented, conscientious, and able to follow instructions and have the ability to communicate in a clear, concise manner, both orally and in writing.

Outstanding UA benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; state and optional retirement plans; access to UA recreation and cultural activities; and more!

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• Perform in vivo physiological examination to animals including, but not limited to: echocardiography, treadmill, Doppler, blood pressure.
  Isolation of mouse vessels, including the aorta, coronary artery, and perform vasodilation studies with myography.
• Perform animal experiments (survival surgical procedure, e.g., contrast echocardiography, echocardiography, Doppler, treadmill, blood pressure measurement with a catheter) and data analysis.
• Measure the myocardial blood flow in vivo.
• Remain updated on literature of the related research topic and develop the projects align with the PI's research focus.
• Plan, coordinate, and conduct scientific research requiring judgment in the independent evaluation, selection, and substantial adaption and modification of standard scientific techniques.
• Design, perform, and/or oversees experiments and data collection to ensure data integrity, quality control, and protocol compliance.
• Perform aspects related to cellular and molecular biology research that include, but are not limited to: bulk RNA-sequencing, scRNA-sequencing, bioinformatics, qRT-PCR, Immunoblotting, proteomics and metabolomics, and Immunocytofluorescence, 3D-imaging (micro-CT and light sheet), primary cell isolation and culture, seahorse analysis, flowcytometry, molecular cloning.
• Attend and present research finding at regular group meetings and scientific conferences.
• Manage daily laboratory operations, including manage, maintain, and order laboratory equipment and supplies; lab inventories and respond to administrative request and procedures.
• Guide the work of others and/or provides guidance to a specialized laboratory or research area.
• Serve as the bio-safety and chemical safety officer for TCRC, including the management of all lab safety and approval protocols.
• Develop and maintain detailed records of experiments, back the original data.
• Analyze data with statistical tools and writing findings narrative reports as appropriate.
• Prepare manuscripts for publication.
• Participate in the acquisition of research funding by initiating and writing grant proposals as appropriate.
• Assist with preparation of grants from the lab.

Knowledge, Skills, and Abilities:

• Knowledge of In vivo physiological animal studie.
• Knowledge of microvessel isolation and myograph.
• Knowledge of molecular and cellular biology.
• Skilled in grant writing and manuscript preparation.

• Bachelor's degree or equivalent advanced learning attained through professional level experience required.
• Minimum of five (5) years of relevant work experience, or equivalent combination of education and work experience.

College of Medicine-Phoenix, Office of Human Resources

HR-PHX@arizona.edu

Application: The online application should be completed in its entirety. Blank or missed information may be considered an incomplete submission.

Letter of Interest: Should clearly indicate how your skills and professional employment experience meet the Minimum and the Preferred qualifications (if applicable).