Postdoctoral Research Scholar

The Weber Laboratory in the Department of Microbiology and Immunology at the University of Iowa isseeking a highly motivated postdoctoral scholar to investigate host-pathogen interactions and bacterialeffector biology during Chlamydia trachomatis infection. Our research focuses on understanding howchlamydial effector proteins promote intracellular survival, immune evasion, and pathogenesis. Currentprojects examine how chlamydial inclusion membrane (Inc) proteins and secreted effectors manipulatecentrosome duplication, nucleocytoplasmic transport, vesicle trafficking, and innate immune signalingduring infection.

Current projects focus on defining how chlamydial effectors reprogram host cell architecture and signalingpathways, how infection disrupts centrosome homeostasis and contributes to multinucleation andchromosomal instability, and how Inc proteins coordinate interactions at the host-pathogen interface tosupport bacterial replication and persistence.

Research in the laboratory integrates microbiology, cell biology, immunology, biochemistry, microbialgenetics, CRISPR-based engineering and screens, advanced fluorescence and live-cell microscopy,proteomics, and animal models of infection. The successful candidate will join an active and collaborativeresearch environment with opportunities to develop independent projects, publish impactful work, present at national and international meetings, and mentor trainees.

Applicants should have a Ph.D. or M.D./Ph.D. degree with a strong background in microbiology, cellbiology, molecular biology, biochemistry, or immunology. Candidates with experience in microbialgenetics, microscopy, infection models, or biochemical approaches are especially encouraged to apply.

The ideal candidate will have a strong publication record, excellent communication skills, and the abilityto work both independently and collaboratively. Compensation will be commensurate with experienceand follow current NIH guidelines.