New

Director, Medical Affairs (Pain)

Vertex Pharmaceuticals Incorporated
vision insurance, paid time off, tuition reimbursement, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Jan 30, 2026
Job Description Job Title Director, Medical Affairs - Pain Department Medical Affairs Location Boston, MA, United States General Summary The Director, Medical Affairs - Pain will provide strategic medical leadership and oversees the development and execution of medical strategies and plans for acute pain management in the U.S. region under the guidance of the Senior Medical Director. This role will focus on fostering scientific exchange, supporting evidence generation and scientific communications, and advancing disease education while ensuring compliance with regulatory and ethical standards. Additionally, the Director will play a key role in supporting and developing team members, including Scientific and Medical Associate/Directors, to ensure professional growth and alignment with organizational goals. Key Duties and Responsibilities Develop and implement medical affairs strategies and lifecycle management plans for acute pain products, ensuring alignment with corporate objectives. Build and maintain relationships with clinical thought leaders (TL's), healthcare professionals, and other stakeholders to gather insights and support scientific exchange in the field of acute pain. Provide scientific input and expertise as a medical reviewer for global medical, commercial, regulatory, and reimbursement documents. Contribute to the development of clinical value narratives through evidence generation and scientific communication. Ensure compliance with corporate and industry guidelines for scientific and medical communication with external stakeholders. Collaborate with cross-functional teams, including Medical Communications, HEOR/Market Access, Marketing, Clinical Development, Regulatory, and Corporate Communications, to align medical strategies with broader organizational goals. Oversee the development and execution of medical education programs, advisory boards, and scientific symposia focused on acute pain management. Monitor and analyze emerging scientific and clinical data related to acute pain to inform product strategies and address competitor threats. Support and mentor team members, including Associate Scientific and Medical Directors, to enhance their professional development and ensure alignment with organizational objectives. Provide guidance and expertise to team members in the development and execution of medical strategies and initiatives. Required Qualifications PharmD, PhD, or Medical degree (MD or equivalent, e.g., DO) required. MD candidates should have completed US residency with board certification and US clinical experience Minimum of 4-6 years of experience in the pharmaceutical or biotechnology industry, with at least 4 years in progressive Medical Affairs role. Proven experience in acute pain management or related therapeutic areas highly preferred Demonstrated expertise in lifecycle clinical trial strategy and execution, scientific communication, and stakeholder engagement. Strong understanding of the U.S. healthcare system, regulatory environment, and market access landscape. Experience in mentoring and supporting the professional development of team members, including Associate Scientific and Medical Directors. Technical Skills Required Proficiency in analyzing and interpreting clinical and scientific data, including pre-clinical and clinical research findings. Advanced knowledge of biostatistics, clinical study design, and research methodologies. Expertise in developing and reviewing medical and scientific content for various stakeholders. Strong communication and presentation skills for engaging with internal and external audiences. Familiarity with government and industry guidelines for medical and scientific exchange. Preferred Skills Experience in developing and executing launch strategies for new products. Advanced negotiation skills and the ability to resolve conflicts constructively. Proven ability to synthesize insights from multiple data sources to inform strategic decisions. Benefits Competitive salary and performance-based bonuses. Comprehensive health, dental, and vision insurance. 401(k) retirement savings plan with company match. Generous paid time off and holiday schedule. Professional development opportunities and tuition reimbursement. Employee wellness programs and resources. Company Information Vertex is a global biotechnology company committed to transforming the lives of people with serious diseases. We are dedicated to scientific innovation and fostering a diverse, inclusive workplace where employees can thrive. Flex Designation On-site or Hybrid (3 days in Boston office with either Monday or Friday as a required day in office) Pay Range: $216,000 - $324,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com