Sr. Research Associate 1

BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients' lives.

• You will assist in the design and execution of studies to enable continuous process improvements of BioMarin's manufacturing purification processes.
• Working with other scientists in the team, you will operate bench scale filtration, chromatography (on AKTA systems) and tangential flow filtration for routine commercial manufacturing support.
• You will perform analytical assays (HPLC, SDS-PAGE, western blot, microtiter plate assays) related to experimental studies.
• You will support investigations that help us understand and resolve complex manufacturing issues and assess their potential impact to product quality.
• You will evaluate raw materials for use in commercial manufacturing processes.
• You will have opportunities to evaluate novel technologies that will support current and future manufacturing processes.
• As a researcher, you will document experimental data, interpret results and support data analysis. You will also assist in writing memorandums, protocols and reports.
• You will contribute to safety, 6S and sustainability efforts in the lab.

• Bench scale purification experience on AKTA system (including column packing and chromatography).
• Knowledge of analytical assays (HPLC, SDS-PAGE, western blot, microtiter plate assays) is a plus.
• Experience with troubleshooting of purification processes.
• Accurate documentation of experimental work, data analysis and results.
• Demonstrated record of strong communication skills (oral and written).
• Proficient with MS Office, Excel, PowerPoint.
• Experience with statistical software (e.g., JMP) is a plus.
• Must be willing to work on multiple projects.
• A strong team player with good collaborative and people skills.
• Strong organization and prioritization skill, with attention to details and ability for in-depth research and analysis.
• Highly motivated with the ability to resolvetechnical issues, develop and implement corrective solutions, be able to quickly adapt and respond effectively to changes.

• B.S. degree in Chemical/Biochemical/Biomedical Engineering or related disciplines with 6+ years experience in process development or manufacturing sciences.
• M.S. degree in Chemical/Biochemical/Biomedical Engineering or related disciplines with 4+ years of experience.

• This role is primarily onsite (5 days a week, 8-hour days) with occasional evening or weekend work required.

• This role is primarily a laboratory position; contact with chemicals is part of the job. The employee will be trained to use common lab equipment and minimize exposure to hazards. Desktop or laptop computer work is also a major component of the job.
• The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
• While performing the duties of this job, the employee is occasionally exposed to work near moving mechanical parts; fumes or airborne particles; toxic or caustic chemicals; risk of electrical shock and vibration. The noise level in the work environment is usually moderate.
• The employee may frequently be required to sit and talk or hear. The employee is occasionally required to stand; walk; use hands to handle or feel; reach with hands and arms; climb or balance; stoop, knee crouch, or crawl. The employee must occasionally lift and/or move up to 25 pounds.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.

• Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.